Nevner at vibrasjon (47Hz) øker blodsirkulasjonen i huden pga stimuli av NO i blodkar cellene. De viste dette fordi ved å gi forsøksdyrene en NO-hemmer fikk de ingen økning i blodsirkulasjon selv med vibrasjoner.
Studies in healthy volunteers and patients with renal failure have shown that vibration, applied with a frequency of 47 Hz and a vibrational intensity of 600 mVpp, increases microcirculation of blood in the skin.
Vibration significantly increased the blood flow at 5 and 15 minutes after application (P = 0.002 and P = 0.046, respectively). Differences between the control and experimental group also were statistically significant (P = 0.0017 and P = 0.046, respectively).
When NO synthase inhibitor L-NAME was administered, the increase in blood flow in the vibration group was minimal after 5 and 10 minutes, and nonexistent after 15 minutes.