Om at området med smerte får en mindre størrelse i Primary Sensory Cortex (S1) i hjernen.

http://www.bodyinmind.org/crpscan-pain-change-our-brain-maps/

That S1 reorganises with pain, and the S1 representation of the CRPS-affected hand is smaller, is widely assumed and accepted.

We found consistent evidence that the representation of the CRPS-affected hand in S1 is smaller than that of the unaffected hand, and that of healthy pain-free controls.