Denne beskriver alt om hvordan johannesurt olje kan brukes på huden:
Topical St. Johnʼs wort preparations such as oils or tinctures are used for the treatment of minor wounds and burns, sunburns, abrasions, bruises, contusions, ulcers, myalgia, and many others.
Denne beskriver hvordan johannesurt olje øke helbredelsen av sår i huden og reduserer betennelsesreaksjoner.
Although the anti-inflammatory effect of the Hypericum extracts was attributed mainly to the inhibitory action of quercetin upon the signal transduction pathway, recent experiments reveal an important role of hyperforin, demonstrating an inhibitory effect upon the lymphocyte reaction at the level of the epidermal cells and upon the T-lymphocyte proliferation . Hyperforin also interferes with prostanoid generation in biological systems, particularly with key enzymes participating in prostaglandin (PG) E2 biosynthesis, i.e., cyclooxygenases (COX)-1/2 and microsomal PGE2 synthase (mPGES)-1 which play key roles in inflammation and tumorigenesis . On the other hand, hyperforin is one of the natural compounds with a strong inhibitory effect upon cyclooxygenase-1 (COX-1) and lipoxygenase-5 (LOX-5) . This dual mechanism offers the rational basis for the traditional use of St. John’s wort in inflammatory dermal disorders.
The wound healing process is evident in all the three types of dermal affection: incision, excision, and thermal burn.
The clinical and histopathological results, along with the wound contraction rate and period of epithelialization, demonstrate the wound-healing effect of the novel St. John’s wort ointment in linear incisions, circular excisions and thermal burns. The results are clearly superior to those cited in other studies.