Gjennomgang av studier på PEA mot smerter som følge av nerver i klem. Ved 600mg daglig har man best og raskest effekt, men 300mg daglig gir også noe. Det tar bare lenger tid.
In total, eight clinical trials have been published in such entrapment syndromes, and 1,366 patients have been included in these trials. PEA proved to be effective and safe in nerve compression syndromes. In one pivotal, double blind, placebo controlled trial in 636 sciatic pain patients, the number needed to treat to reach 50% pain reduction compared to baseline was 1.5 after 3 weeks of treatment. Furthermore, no drug interactions or troublesome side effects have been described so far.