Om fibromyalgi og at 41% av pasientene har tynnfibernevropati. 3% av kontrollgruppen har det. Tynnfibernevropati-type smerter er en del av mange sykdommer og flere studier viser at det er underdiagnostisert.
No specific objective abnormalities have been identified, which precludes definitive testing, disease-modifying treatments, and identification of causes.
We found that 41% of skin biopsies from subjects with fibromyalgia vs 3% of biopsies from control subjects were diagnostic for SFPN, and MNSI and UENS scores were higher in patients with fibromyalgia than in control subjects (all P⩽0.001).
Abnormal AFTs (autonomic function test) were equally prevalent, suggesting that fibromyalgia-associated SFPN is primarily somatic.
These findings suggest that some patients with chronic pain labeled as fibromyalgia have unrecognized SFPN, a distinct disease that can be tested for objectively and sometimes treated definitively.