To studier på hvordan huden påvirker trykksensitivitet.

Ene nevner at trykkømhet i fibromyalgi er værst over der en nerve er, ikke så mye over knokler eller muskler.  Nevner at en bedøvende krem på huden ikke endrer trykkømhet.

Andre nevner at trykkømhet normalt faktisk blir mindre av en bedøvende krem, og bekrefter at ømheten er større over en nervebane enn over knokkel eller muskel.

Increased pressure pain sensibility in fibromyalgia patients is located deep to the skin but not restricted to muscle tissue

http://www.sciencedirect.com/science/article/pii/0304395996000127

The site with underlying nerve had a lower PPT than the bony site (P > 0.001) and the ‘pure’ muscle site (P > 0.001), respectively. These relations remained unaltered by skin hypoesthesia.

Application of EMLA, compared to control cream, did not change PPTs over any area examined. The results demonstrated that pressure-induced pain sensibility in FM patients is not most pronounced in muscle tissue and does not depend on increased skin sensibility.

Pressure pain thresholds in different tissues in one body region. The influence of skin sensitivity in pressure algometry.

http://www.ncbi.nlm.nih.gov/m/pubmed/10380724

The PPT was significantly (p < 0.001) lower at the «muscle/nerve» site than at the bony and «pure» muscle sites.

However, PPTs after control cream were lower (p < 0.001) over all examined areas than those obtained prior to cream application. Thus, EMLA cream increased PPTs compared to control sites in all examined areas (p < 0.001). Under the given circumstances, skin pressure pain sensitivity was demonstrated to influence the PPT.