Lactic acid buffering, nonmetabolic CO2 and exercise hyperventilation: a critical reappraisal

Om non-metabolic CO2, altså CO2 som ikke skapes i mitokondriene men kommer fra bikarbonat-reaksjoner med melkesyre.

www.ncbi.nlm.nih.gov/pubmed/15890562‎
Hele studien i dropbox: https://dl.dropboxusercontent.com/u/17457302/Nonmetabolic_CO2.pdf

«It has been suggested that hyperventilation and the disproportionate increase in VCO2 versus VO2 above the ventilatory threshold (V(TH)) in ramp exercise are due to the production of nonmetabolic CO2 in muscle because of lactic acid buffering by plasma bicarbonate entering the cell in exchange with lactate»

«(1) bicarbonate is not the main buffer in the muscle; (2) the decrease in standard bicarbonate concentration is not the mirror image of the increase in lactate concentration; (3) buffering by bicarbonate does not increase CO2 production in muscle (no nonmetabolic CO2 is produced in tissues); (4) the CO2 flow to the lungs, which should not be confused with VCO2 at the mouth, does not increase at a faster rate above than below V(TH).»

Forklaring på Non-Metabolic CO2 her:

Non-Metabolic Carbon Dioxide

At rest and during moderate exercise, lactic acid will not increase in your muscles because all that is produced is also used. Once you reach more challenging work rates, production exceeds use and the acid enters your blood. To maintain a healthy pH, sodium bicarbonate in your blood buffers most lactic acid by breaking it down to water and carbon dioxide. This results in additional carbon dioxide that must be released by your blood.

Read more: http://www.livestrong.com/article/524672-what-effect-does-exercise-have-on-the-amount-of-carbon-dioxide-released-by-the-blood/#ixzz2SmWggmYh

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