Pain Sensitivity and Recovery From Mild Chronic Sleep Loss

Denne viser at økt søvnmengde reduserer smerte. Ved å øke antall timer søvn fra (under) 8 timer til 10 timer ble deltakerene mindre sensitive for smertestimuli. Den nevner også at vi sover mindre nå enn vi gjorde på 60-tallet. Nå er vi nede i 6 timer eller mindre, mens på 60-tallet sov vi 8 timer eller mindre. Den nevner også vi vi får 24%-31% mindre smertetåleranse om vi får 50% dårligere søvn 1 enkelt natt.

Studien beskriver at 4 dager med 10 timers søvn reduserer smertesensitivitet med 25%.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490359/

Abstract

Study Objectives:

To determine whether an extended bedtime in sleepy and otherwise healthy volunteers would increase alertness and thereby also reduce pain sensitivity.

Setting:

Outpatient with sleep laboratory assessments.

Participants and Interventions:

Healthy volunteers (n = 18), defined as having an average daily sleep latency on the Multiple Sleep Latency Test (MSLT) < 8 min, were randomized to 4 nights of extended bedtime (10 hr) (EXT) or 4 nights of their diary-reported habitual bedtimes (HAB). On day 1 and day 4 they received a standard MSLT (10:00, 12:00, 14:00, and 16:00 hr) and finger withdrawal latency pain testing to a radiant heat stimulus (10:30 and 14:30 hr).

Results:

During the four experimental nights the EXT group slept 1.8 hr per night more than the HAB group and average daily sleep latency on the MSLT increased in the EXT group, but not the HAB group. Similarly, finger withdrawal latency was increased (pain sensitivity was reduced) in the EXT group but not the HAB group. The nightly increase in sleep time during the four experimental nights was correlated with the improvement in MSLT, which in turn was correlated with reduced pain sensitivity.

Conclusions:

These are the first data to show that an extended bedtime in mildly sleepy healthy adults, which resulted in increased sleep time and reduced sleepiness, reduces pain sensitivity.

In the 1960s sleep duration was estimated to be approximately 8 hr per 24-hr period, whereas by 2005 it was reported that sleep duration was 7 hr or less.3 A national survey reported that 21% of the population obtains 6 hr or less of sleep per 24-hr period.4

Partial deprivation, the reduction of bedtime by 50% for one night, reduced finger withdrawal latency (increased pain sensitivity) to a radiant heat stimulus by 24%.7

In the EXT group of the current study finger withdrawal latency was increased by 25%, which reflects a reduction in pain sensitivity.

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